Using an experimental model to simulate the blood-brain barrier, scientists reported in unprecedented detail how antioxidants protect the brain from inflammation caused by such neurodegenerative diseases as Alzheimer's and Parkinson's.
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Wednesday, June 30, 2021
Employed individuals more likely to contract the flu, study shows
Researchers found that employed individuals, on average, are 35.3% more likely to be infected with the flu virus.
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Embryo freezing for IVF appears linked to blood pressure problems in pregnancy
A large cohort study drawn from the national IVF registry of France, which included almost 70,000 pregnancies delivered after 22 weeks gestation between 2013 and 2018, has found a higher risk of pre-eclampsia and hypertension in pregnancies derived from frozen-thawed embryos. This risk was found significantly greater in those treatments in which the uterus was prepared for implantation with hormone replacement therapies. The results confirm with real-life data what has been observed in sub-groups of patients in other studies.
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Astronauts demonstrate CRISPR/Cas9 genome editing in space
Researchers have developed and successfully demonstrated a novel method for studying how cells repair damaged DNA in space.
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How plants quickly adapt to shifting environmental conditions
Researchers offers a new understanding of how gene activity directs plant growth, and how quickly plants respond to their environment -- with shifting light conditions triggering molecular changes in as little as five minutes. The findings provide insights into how to increase yield and safeguard world food production as climate change shrinks the planet's arable land.
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Antibiotic-resistant bacteria found in cattle
New research shows that there may be more antimicrobial-resistant salmonella in our food animals than scientists previously thought.
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Common errors in internet energy analysis
When it comes to understanding and predicting trends in energy use, the internet is a tough nut to crack. So say energy researchers in two recent articles that discuss the pitfalls that plague estimates of the internet's energy and carbon impacts.
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'Plugging in' to produce environmentally friendly bioplastics
Bioplastics -- biodegradable plastics made from biological substances rather than petroleum -- can be created in a more economical and environmentally friendly way from the byproducts of corn stubble, grasses and mesquite agricultural production, according to a new study.
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A future ocean that is too warm for corals might have half as many fish species
Predicting the potential effects of coral loss on fish communities globally is a fundamental task, especially considering that reef fishes provide protein to millions of people. A new study predicts how fish diversity will respond to declines in coral diversity and shows that future coral loss might cause a more than 40% reduction in reef fish diversity globally.
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NIST laser 'comb' systems now measure all primary greenhouse gases in the air
Researchers at NIST have upgraded their laser frequency-comb instrument to simultaneously measure three airborne greenhouse gases -- nitrous oxide, carbon dioxide and water vapor -- plus the major air pollutants ozone and carbon monoxide.
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Better method to predict offshore wind power
Researchers have developed a machine learning model using a physics-based simulator and real-world meteorological data to better predict offshore wind power.
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Mixing it up: A low-cost way to make efficient, stable perovskite solar cells
By using a fluid mixing process instead of expensive, high-temperature fabrication methods, researchers may have demonstrated a pathway to producing flexible, printed solar cells on a cost effective, industrial scale.
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New research lifts the clouds on land clearing and biodiversity loss
A new mathematical model has been developed to uncover land clearing when satellite imagery is obstructed by clouds.
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The Southern diet - fried foods and sugary drinks - may raise risk of sudden cardiac death
Participants in a large-scale study who more commonly consumed a Southern-style diet - high in added fats, fried foods, processed meats and sugary drinks - had a higher risk of sudden cardiac death than people who had lower adherence to a Southern-style diet.
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Discovery of the role of a key gene in the development of ALS
Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis. The loss of function of an important gene, C9orf72, may affect communication between motor neurons and muscles in people with this disease.
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Digging into the molecules of fossilized dinosaur eggshells
Dinosaurs roamed the Earth more than 65 million years ago, and paleontologists and amateur fossil hunters are still unearthing traces of them today. The minerals in fossilized eggs and shell fragments provide snapshots into these creatures' early lives, as well as their fossilization processes. Now, researchers have analyzed the molecular makeup of fossilized dinosaur eggshells from Mexico, finding nine amino acids and evidence of ancient protein structures.
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Fecal records show Maya population affected by climate change
A new study has shown that the size of the Maya population in the lowland city of Itzan (in present-day Guatemala) varied over time in response to climate change. The findings show that both droughts and very wet periods led to important population declines.
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The Southern diet - fried foods and sugary drinks - may raise risk of sudden cardiac death
Participants in a large-scale study who more commonly consumed a Southern-style diet - high in added fats, fried foods, processed meats and sugary drinks - had a higher risk of sudden cardiac death than people who had lower adherence to a Southern-style diet.
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Slowing down grape ripening can improve fruit quality for winemaking
Wine grapes are particularly finicky when it comes to their environment. For instance, heatwaves and droughts lead to earlier berry ripening and lackluster wine. And these types of episodes are expected to intensify as Earth's climate changes. Now, researchers have tweaked growing conditions for Cabernet Sauvignon grapes to slow down their ripening, which increased the levels of compounds associated with wine's characteristic floral and fruity notes.
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Jackdaws don't console traumatized mates
Male jackdaws don't stick around to console their mate after a traumatic experience, new research shows.
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Turning plastic into foam to combat pollution
Researchers have developed a method to turn biodegradable plastic knives, spoons, and forks into a foam that can be used as insulation in walls or in flotation devices. The investigators placed the cutlery into a chamber filled with carbon dioxide. As pressure increased, the gas dissolved into the plastic. When they suddenly released the pressure in the chamber, the carbon dioxide expanded within the plastic, creating foaming.
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Frequent COVID-19 testing key to efficient, early detection, study finds
The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98 percent sensitivity if deployed at least every three days.
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Researchers look to human 'social sensors' to better predict elections and other trends
Researchers can gather highly accurate information about social trends and groups by asking about a person's social circle rather than interrogating their own individual beliefs.
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Tuesday, June 29, 2021
This 5,000-year-old man had the earliest known strain of plague
The oldest strain of Yersinia pestis -- the bacteria behind the plague that caused the Black Death, which may have killed as much as half of Europe's population in the 1300s -- has been found in the remains of a 5,000-year-old hunter-gatherer. A genetic analysis reveals that this ancient strain was likely less contagious and not as deadly as its medieval version.
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Increased use of household fireworks creates a public health hazard
Fireworks are synonymous in the United States with the celebration of Independence Day and other special events, but the colorful displays have caused a growing risk to public safety in recent years, according to a new study.
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Computer training program for seniors can reduce hazardous driving
A recent proof-of-concept study finds that a low-cost training program can reduce hazardous driving in older adults. Researchers hope the finding will lead to the training becoming more widely available.
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A new class of functional elements in the human genome?
When regions of the human genome where the DNA can fold into unusual three-dimensional structures called G-quadruplexes (G4s) are located in regulatory sequences or other functional, but non-protein coding, regions of the genome, they are maintained by selection, are more common, and their unusual structures are more stable. Together, these lines of evidence suggest that G4 elements should be added to the list of functional elements of the genome.
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Drug relieves persistent daydreaming, fatigue, and brain sluggishness in adults with ADHD
Tests of a drug known to stimulate brain activity have shown early success in reducing symptoms of sluggish cognitive tempo in 38 men and women with attention deficit hyperactivity disorder (ADHD.)
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'Unlocking' the potential of viruses to fight cancer
Researchers have elucidated the mechanism through which the H-1PV cancer-destroying virus can cause cell lysis and death. At the heart of this process lie laminins, and specifically laminin gamma 1, a family of proteins on the surface of a cancer cell to which this virus binds. The findings carry significant implications for the advancement of virus-based anticancer strategies and for the prediction of a patient's response to this innovative therapeutic approach.
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Monday, June 28, 2021
'Unexciting' an anxious brain: Novel drug reduces anxiety-like behavior in mice
Anxiety is considered a natural response to stress. However, a state of heightened anxiety, called anxiety disorder, prevents thousands of people from living their best lives. While several underlying mechanisms have been therapeutically targeted, much remains to be discovered about this disorder. In an effort to get closer to unraveling the mechanisms that govern this condition, researchers have identified a drug that reduces glutamate-induced neurotransmission, involved in anxiety-like behavior.
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Hundreds of lives saved in Kansas counties that adopted mask mandates, study finds
New research shows that despite cultural and political pushback, the evidence remains clear: Face masks made a difference in Kansas.
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New study sheds light on evolution of photosynthesis
A new study sheds new light on the evolution of photosynthesis in plants and algae, which could help to improve crop production.
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Weird warbler reveals genetics of its mismatched colors
An incredibly rare hybrid warbler with mismatched color patterns has allowed researchers to disentangle the genetic drivers of two traits that usually come as a package deal -- the black face mask and the black throat patch in blue-winged and golden-winged warblers.
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Storing carbon inn rocks underground: Old oil fields may be less prone to induced earthquakes
Subsurface carbon sequestration -- storing carbon in rocks deep underground -- offers a partial solution for removing carbon from the atmosphere. Used alongside emissions reductions, geologic carbon sequestration could help mitigate anthropogenic climate change. But like other underground operations, it comes with risks -- including earthquakes.
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How to build a better wind farm
Location, location, location -- when it comes to the placement of wind turbines, the old real estate adage applies, according to new research.
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COVID-19 vaccine generates immune structures critical for lasting immunity
The first two COVID-19 vaccines authorized for emergency use by the U.S. Food and Drug Administration (FDA) employed mRNA technology, which had never before been used in FDA-approved vaccines. A new study has found evidence that the immune response to such vaccines is both strong and potentially long-lasting.
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New molecule found in chestnut leaves disarms dangerous staph bacteria
Scientists isolated a molecule, extracted from the leaves of the European chestnut tree, with the power to neutralize dangerous, drug-resistant staph bacteria.
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New technique to treat middle ear infections
In a new study, researchers have designed a miniaturized 3D-printed device to inactivate Pseudomonas aeruginosa, a common bacterium that causes the infection.
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GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration
GluN3A-deficient mice display all aspects of Alzheimer's neurodegeneration.
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New molecule found in chestnut leaves disarms dangerous staph bacteria
Scientists isolated a molecule, extracted from the leaves of the European chestnut tree, with the power to neutralize dangerous, drug-resistant staph bacteria.
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Mountaintop glacier ice disappearing in tropics around the world
Mountaintop glacier ice in the tropics of all four hemispheres covers significantly less area -- in one case as much as 93% less -- than it did just 50 years ago, a new study has found.
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Most nitrogen in Gulf of Mexico comes from coastal waters
Almost all of the nitrogen that fertilizes life in the open ocean of the Gulf of Mexico is carried into the Gulf from shallower coastal areas, researchers found.
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GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration
GluN3A-deficient mice display all aspects of Alzheimer's neurodegeneration.
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Plant physiology: A tale of three proteins
Biologists have shown that 'supervisor' and 'motivator' proteins are required to enable a third factor to perform its function in photosynthesis.
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Mangrove forest study has takeaways for coastal communities
A new article shines light on the effect human-made infrastructure and natural topography has on coastal wetlands after major storm events.
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DNA data and modelling reveal potential spread of invasive species
Scientists have found that a marine invasive species - a sea squirt that lives on rocky shores - could spread along 3,500 kilometers of South American coastline if climate change or human activities alter sea conditions.
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Striking gold: Synthesizing green gold nanoparticles for cancer therapy with biomolecules
Scientists have designed an eco-friendly protocol for synthesizing gold nanoparticles with optimized morphology for near-infrared light absorption using a biomolecule called B3 peptide. They report the synthesis of triangular and circular gold nanoplates and their effectiveness in killing cancer cells by converting the absorbed light into heat, providing useful insights for the development of non-invasive cancer therapy.
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Deep machine learning completes information about the bioactivity of one million molecules
A newly developed tool predicts the biological activity of chemical compounds, key information to evaluate their therapeutic potential. Using artificial neural networks, scientists have inferred experimental data for a million compounds and have developed a package of programs to make estimates for any type of molecule.
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Blood stem cells make brain tumors more aggressive
Scientists have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These hematopoietic stem cells promote division of the cancer cells and at the same time suppress the immune response against the tumor. This surprising discovery might open up new possibilities for developing more effective immunotherapies against these malignant brain tumors.
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Love: How the feeling of power determines happy relationships
Want to have a happy relationship? Make sure both partners feel they can decide on issues that are important to them. Objective power measured by income, for example, doesn't seem to play a big role, according to a new study. Instead, how lovers perceive power dynamics in their relationship is most important for relationship satisfaction.
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Fast IR imaging-based AI identifies tumor type in lung cancer
The prognosis and effective therapies differ based on the type of lung cancer. While it previously took several days to precisely determine the underlying mutation, a research team has been able to reliably perform this determination in just one step using a combination of quantum cascade laser-based infrared microscopy and artificial intelligence.
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New tools for pandemic prevention research: DNA sequencing from water and leeches
In new research, water from African and Mongolian waterholes as well as bloodmeals from Southeast Asian leeches were assessed for the ability to retrieve mammalian viruses without the need to find and catch the mammals. The scientists analyzed the samples using high-throughput sequencing to identify known viruses as well as viruses new to science.
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Males help keep populations genetically healthy
A few males are enough to fertilize all the females. The number of males therefore has little bearing on a population's growth. However, they are important for purging bad mutations from the population. This is shown by a new study providing in-depth knowledge of the possible long-term genetic consequences of sexual selection.
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Test distinguishes SARS-CoV-2 from other coronaviruses with 100-percent accuracy
Researchers have demonstrated a tablet-sized device that can reliably detect multiple COVID-19 antibodies and biomarkers simultaneously. Initial results show the test can distinguish between antibodies produced in response to SARS-CoV-2 and four other coronaviruses with 100-percent accuracy. The researchers are now working to see if the easy-to-use, energy-independent, point-of-care device can be used to predict the severity of a COVID-19 infection or a person's immunity against variants of the virus.
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Test distinguishes SARS-CoV-2 from other coronaviruses with 100-percent accuracy
Researchers have demonstrated a tablet-sized device that can reliably detect multiple COVID-19 antibodies and biomarkers simultaneously. Initial results show the test can distinguish between antibodies produced in response to SARS-CoV-2 and four other coronaviruses with 100-percent accuracy. The researchers are now working to see if the easy-to-use, energy-independent, point-of-care device can be used to predict the severity of a COVID-19 infection or a person's immunity against variants of the virus.
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Sunday, June 27, 2021
Elephants solve problems with personality
This study makes connections between two sources of individual variation, personality and cognition, in threatened species.
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Researchers find the adhesions that build the brain's networks
Researchers have discovered a crucial protein involved in the communication and coordination between astrocytes as they build synapses in the brain. Lacking this molecule, called hepaCAM, astrocytes aren't as sticky as they should be, and tend to stick to themselves rather than forming connections with their fellow astrocytes.
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Saturday, June 26, 2021
Potential new CAR-T cell therapy for multiple myeloma
Researchers are studying a potential new chimeric antigen receptor-T cell therapy (CAR-T cell therapy) treatment for multiple myeloma.
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Differences in human, mouse brain cells have important implications for disease research
A study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.
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Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep
Biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop new methods of treatment.
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Scientists use NASA satellite data to track ocean microplastics from space
Scientists have developed an innovative way to use NASA satellite data to track the movement of tiny pieces of plastic in the ocean.
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Having the same nurse for home health visits may prevent rehospitalization for people with dementia
People with dementia receiving home health care visits are less likely to be readmitted to the hospital when there is consistency in nursing staff, according to a new study.
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More intense predation in the tropics can limit marine invasions
Marine biologists tested predictions about biological invasions, first in Panama and then in an experiment of unprecedented geographic scale.
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Engineered yeast could expand biofuels' reach
Researchers found a way to reduce cellulosic feedstocks' toxicity to yeast, making it feasible to use these abundant feedstocks to produce ethanol, biodiesel, or bioplastics.
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Friday, June 25, 2021
Environmental impact of hydrofracking vs. conventional gas/oil drilling: Research shows the differences may be minimal
Researchers have developed a new machine learning technique to holistically assess water quality data in order to detect groundwater samples likely impacted by recent methane leakage during oil and gas production. Using that model, the team concluded that unconventional drilling methods like hydraulic fracturing do not necessarily incur more environmental problems than conventional oil and gas drilling.
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Study confirms the low likelihood that SARS-CoV-2 on hospital surfaces is infectious
A new study confirms the low likelihood that coronavirus contamination on hospital surfaces is infectious. The study is the original report on recovering near-complete SARS-CoV-2 genome sequences directly from surface swabs.
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Leopard gecko skin tumors traced to cancer gene
In a rare gecko color variety known as Lemon Frost, scientists have traced an unusual coloring and tendency to form tumors to a gene linked to human melanoma.
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Glial cells help mitigate neurological damage in Huntington's disease
Glia affected by Huntington's disease respond by tuning down synapse genes, which has a protective effect.
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Membrane proteins of bacteria and humans show surprising similarities
The cells of simple organisms, such as bacteria, as well as human cells are surrounded by a membrane, which fulfills various tasks including protecting the cell from stress. Researchers have now discovered that a membrane protein found in bacteria has a similar structure and function as a group of proteins that are responsible for remodeling and rebuilding the cell membrane in humans. No connection between the two protein groups was known before.
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How neurons get past 'no'
A new study shows that inhibitory neurons do more than just inhibit neuron activity like an off-switch; paradoxically, they actually increase the amount of information transmitted through the nervous system.
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People with fibromyalgia are substituting CBD for opioids to manage pain
As the ravages of the opioid epidemic lead many to avoid these powerful painkillers, a significant number of people with fibromyalgia are finding an effective replacement in CBD-containing products, finds a new study.
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Potato and rice protein shakes may be a viable vegan alternative to whey protein shakes, research suggests
A new study found that plant-based protein shakes may be potential viable alternatives to milk-based whey protein shakes, particularly in people with need of careful monitoring of glucose levels.
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Leopard gecko skin tumors traced to cancer gene
In a rare gecko color variety known as Lemon Frost, scientists have traced an unusual coloring and tendency to form tumors to a gene linked to human melanoma.
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Scientists can predict and design single atom catalysts for important chemical reactions
Guided by quantum chemical calculations, scientists design and test a new single atom catalyst that converts propane to propylene with 100% efficiency, with little deactivation by coking. If adopted by industry, the catalyst could save billions of dollars and stop millions of tons of carbon dioxide being emitted into the atmosphere.
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Ethane proxies for methane in oil and gas emissions
Measuring ethane in the atmosphere shows that the amounts of methane going into the atmosphere from oil and gas wells and contributing to greenhouse warming is higher than suggested by the U.S. Environmental Protection Agency, according to an international team of scientists who spent three years flying over three areas of the U.S. during all four seasons.
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Membrane proteins of bacteria and humans show surprising similarities
The cells of simple organisms, such as bacteria, as well as human cells are surrounded by a membrane, which fulfills various tasks including protecting the cell from stress. Researchers have now discovered that a membrane protein found in bacteria has a similar structure and function as a group of proteins that are responsible for remodeling and rebuilding the cell membrane in humans. No connection between the two protein groups was known before.
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Are zebra mussels eating or helping toxic algae?
While invasive zebra mussels consume small plant-like organisms called phytoplankton, researchers discovered during a long-term study that zebra mussels can actually increase Microcystis, a type of phytoplankton known as 'blue-green algae' or cyanobacteria, that forms harmful floating blooms.
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Natural history and conservation importance of Chinese mountain cat
In a large study of Chinese cats, genetic detectives highlight the evolutionary uniqueness and premier conservation importance of the elusive Chinese mountain cat (Felis silvestris bieti), found only in the Tibetan plateau of China.
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A 'tasty' protein may lead to new ways to treat metabolic and immune diseases
The same taste-sensing molecule that helps you enjoy a meal from your favorite restaurant may one day lead to improved ways to treat diabetes and other metabolic and immune diseases. TRPM5 is a specialized protein that is concentrated in the taste buds, where it helps relay messages to and from cells. It has long been of interest to researchers due to its roles in taste perception and blood sugar regulation.
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New CRISPR 3.0 system for highly efficient gene activation in plants
Biologists have introduced a new and improved CRISPR 3.0 system in plants, focusing on gene activation. This third generation system focuses on multiplexed gene activation that can boost the function of multiple genes simultaneously. This system boasts four to six times the activation capacity of current state-of-the-art CRISPR technology, demonstrating high accuracy and efficiency in up to seven genes at once.
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People with fibromyalgia are substituting CBD for opioids to manage pain
As the ravages of the opioid epidemic lead many to avoid these powerful painkillers, a significant number of people with fibromyalgia are finding an effective replacement in CBD-containing products, finds a new study.
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COVID-linked multi-system inflammatory syndrome in children diagnosed more in Black and Latino children
Multisystem Inflammatory Syndrome in Children (MIS-C) significantly affected more Black and Latino children than white children, with Black children at the highest risk, according to a new study. Researchers also found cardiac complications, including systolic myocardial dysfunction and valvular regurgitation, were more common in MIS-C patients who were critically ill.
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Potato and rice protein shakes may be a viable vegan alternative to whey protein shakes, research suggests
A new study found that plant-based protein shakes may be potential viable alternatives to milk-based whey protein shakes, particularly in people with need of careful monitoring of glucose levels.
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Solving a puzzle to design larger proteins
A team has identified the design principles for creating large 'ideal' proteins from scratch, paving the way for the design of proteins with new biochemical functions.
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Thursday, June 24, 2021
Marmoset study identifies brain region linking actions to their outcomes
The 'anterior cingulate cortex' is key brain region involved in linking behaviors to their outcomes. When this region was temporarily silenced, monkeys did not change behavior even when it stopped having the expected outcome. The finding is a step towards targeted treatment of human disorders involving compulsive behavior, such as OCD and eating disorders, thought to involve impaired function in this brain region.
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Researchers find health benefits of Connecticut-grown sugar kelp
Researchers have reported significant findings supporting the nutritional benefits of Connecticut-grown sugar kelp. They found brown sugar kelp (Saccharina latissima) inhibits hepatic inflammation and fibrosis in a mouse model of diet-induced non-alcoholic steatohepatitis, a fatty liver disease.
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An enzyme prevents the formation of multiple heads and axes in freshwater polyp Hydra
In the animal kingdom, specific growth factors control body axis development. They are produced by a small group of cells at one end of the embryo to be distributed in a graded fashion toward the opposite pole. Through this, discrete spatial patterns arise that determine the correct formation of the head-foot axis. Researchers have discovered an enzyme in the freshwater polyp Hydra that shapes this process by limiting the activity of certain growth factors.
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Crops: Mixed cultures for a greater yield
What holds true for meadows would seem to apply to arable land, too: mixed cultures are more fruitful than monocultures.
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Immunologists discover new trick used by MRSA superbug -- may aid vaccine development
New research has uncovered a novel trick employed by the bacterium Staphylococcus aureus to thwart the immune response, raising hopes that a vaccine that prevents deadly MRSA infections is a little closer on the horizon.
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Chemicals from human activities in transplanted oysters far from population centers
Wastewater treatment facilities clean the water that goes down our sinks and flushes our toilets, but they do not remove everything. A recent study detected low levels of pharmaceuticals and personal care product chemicals in oysters the team deployed at various distances from wastewater effluent pipes along the Oregon and Washington coast.
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Marmoset study identifies brain region linking actions to their outcomes
The 'anterior cingulate cortex' is key brain region involved in linking behaviors to their outcomes. When this region was temporarily silenced, monkeys did not change behavior even when it stopped having the expected outcome. The finding is a step towards targeted treatment of human disorders involving compulsive behavior, such as OCD and eating disorders, thought to involve impaired function in this brain region.
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Nanotech and AI could hold key to unlocking global food security challenge
'Precision agriculture' where farmers respond in real time to changes in crop growth using nanotechnology and artificial intelligence (AI) could offer a practical solution to the challenges threatening global food security, a new study reveals.
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Common plant fiber gel doubled rate of tumor eradication
Many people don't realize that the trillions of bacteria, viruses, and fungi residing within the gastrointestinal tract --collectively called the gut microbiome -- are connected to overall health, and specifically to cancer.
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Streptococcus pneumoniae sticks to dying lung cells, worsening secondary infection following flu
Researchers have found a further reason for the severity of dual infection by influenza and Streptococcus pneumonia -- a new virulence mechanism for a surface protein on the pneumonia-causing bacteria S. pneumoniae. This insight comes 30 years after discovery of that surface protein, called pneumococcal surface protein A. This mechanism had been missed in the past because it facilitates bacterial adherence only to dying lung epithelial cells, not to living cells.
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Scientists may need to rethink which genes control aging, study suggests
Researchers fed fruit flies antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally thought control aging. To their surprise, the antibiotics not only extended the lives of the flies but also dramatically changed the activity of many of these genes. Their results suggested that only about 30% of the genes traditionally associated with aging set an animal's internal clock while the rest reflect the body's response to bacteria.
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Non-invasive potential treatment for Alzheimer's disease
Ultrasound can overcome some of the detrimental effects of ageing and dementia without the need to cross the blood-brain barrier, researchers have found.
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A new type of Homo unknown to science
The bones of an early human, unknown to science, who lived in the Levant at least until 130,000 years ago, were discovered in excavations at the Nesher Ramla site, near the city of Ramla. Recognizing similarity to other archaic Homo specimens from 400,000 years ago, found in Israel and Eurasia, the researchers reached the conclusion that the Nesher Ramla fossils represent a unique Middle Pleistocene population, now identified for the first time.
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Water vole genome will help boost conservation of one of UK's most endangered mammals
A new tool to help conserve one of the UK's most threatened mammals has been released today, with the publication of the first high-quality reference genome for the European water vole.
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Protocells spring into action
Scientists with an interest in protoliving technologies, have published research which paves the way to building new semi-autonomous devices with potential applications in miniaturized soft robotics, microscale sensing and bioengineering.
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Throwing shade: Measuring how much trees, buildings cool cities
When the summer sun blazes on a hot city street, our first reaction is to flee to a shady spot protected by a building or tree. A new study is the first to calculate exactly how much these shaded areas help lower the temperature and reduce the 'urban heat island' effect.
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Streptococcus pneumoniae sticks to dying lung cells, worsening secondary infection following flu
Researchers have found a further reason for the severity of dual infection by influenza and Streptococcus pneumonia -- a new virulence mechanism for a surface protein on the pneumonia-causing bacteria S. pneumoniae. This insight comes 30 years after discovery of that surface protein, called pneumococcal surface protein A. This mechanism had been missed in the past because it facilitates bacterial adherence only to dying lung epithelial cells, not to living cells.
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Scientists may need to rethink which genes control aging, study suggests
Researchers fed fruit flies antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally thought control aging. To their surprise, the antibiotics not only extended the lives of the flies but also dramatically changed the activity of many of these genes. Their results suggested that only about 30% of the genes traditionally associated with aging set an animal's internal clock while the rest reflect the body's response to bacteria.
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Preventing the break-in of the toxoplasmosis parasite
Toxoplasma gondii is an obligate intracellular parasite which, to survive, must absolutely penetrate its host's cells. Understanding how the parasite manages to enter host cells offers opportunities to develop more prevention. A team has now identified the key role of RON13, which is essential for the invasion process. The three-dimensional structure and the site of action of this enzyme are atypical, thus offering the possibility of designing specific inhibitors to stop the infection.
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Children's beat gestures predict the subsequent development of their oral skills
New research shows that the early production of beat gestures with the hands (i.e., gestures normally associated with emphasis that do not represent the semantic content of speech) by infants between 14 and 58 months of age in natural interactions with their carers predicts that in their later development, nearing the age of five, these children obtain better results insofar as their oral narrative skills.
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Preventing the break-in of the toxoplasmosis parasite
Toxoplasma gondii is an obligate intracellular parasite which, to survive, must absolutely penetrate its host's cells. Understanding how the parasite manages to enter host cells offers opportunities to develop more prevention. A team has now identified the key role of RON13, which is essential for the invasion process. The three-dimensional structure and the site of action of this enzyme are atypical, thus offering the possibility of designing specific inhibitors to stop the infection.
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Plant Protector: How plants strengthen their light-harvesting membranes against environmental stress
An international study has revealed the structure of a membrane-remodeling protein that builds and maintains photosynthetic membranes. These fundamental insights lay the groundwork for bioengineering efforts to strengthen plants against environmental stress, helping to sustaining human food supply and fight against climate change.
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Cyclone study improves climate projections
Migrating storms and local weather systems known as cyclones and anticyclones were thought to contribute to behaviors and properties of our global weather system. However, the means to probe cyclones and anticyclones were limited. Researchers demonstrated a new three-dimensional analytical methodology that can quantify the way individual cyclones and anticyclones impact broader weather systems. This study aids longer-term circulation and climate studies, including how storm characteristics may change in the future.
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Wednesday, June 23, 2021
East Antarctic summer cooling trends caused by tropical rainfall clusters
A study uncovers a new mechanism linking climate trend in Antarctica to rainfall occurrences in the tropics.
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'Multi-kingdom dialogue' between internal, external microbiota
Scientists have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop.
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Dieting and its effect on the gut microbiome
Researchers were able to show for the first time that a very low calorie diet significantly alters the composition of the microbiota present in the human gut. The researchers report that dieting results in an increase of specific bacteria - notably Clostridioides difficile, which is associated with antibiotic-induced diarrhea and colitis.
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Harvesting drinking water from humid air around the clock
Researchers have developed a condenser for countries where water is in short supply. Theirs is a zero-energy solution for harvesting water from the atmosphere throughout the 24-hour daily cycle. It relies on a self-cooling surface and a special radiation shield.
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Western high-fat diet can cause chronic pain, according to new study
A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a new study.
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Rare genetic defect replicated in fish model
A rare genetic defect that affects the so-called ALG2 gene can cause serious metabolic diseases in humans. Until now, its rareness and complexity made it difficult to study this congenital glycosylation disorder. A research team has finally succeeded in introducing the underlying mutation in the ALG2 gene in a fish model, allowing the causes of these complex diseases to be studied at the molecular level.
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Machine learning aids earthquake risk prediction
Soil liquefaction was a major feature of the 2011 Christchurch, New Zealand earthquake that killed 185 people. Researchers developed a machine learning model to predict the amount of lateral movement that can be expected from liquefaction during a natural hazard event. Their model, trained on Christchurch data, was 70% accurate at determining the amount of displacement that occurred.
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New research reveals remarkable resilience of sea life in the aftermath of mass extinctions
Pioneering research has shown marine ecosystems can start working again, providing important functions for humans, after being wiped out much sooner than their return to peak biodiversity.
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The origins of farming insects more than 100 million years ago
A beetle bores a tree trunk to build a gallery in the wood in order to protect its lay. As it digs the tunnel, it spreads ambrosia fungal spores that will feed the larvae. When these bore another tree, the adult beetles will be the transmission vectors of the fungal spores in another habitat. This mutualism among insects and ambrosia fungi could be more than 100 years old, more than what was thought to date.
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Sneeze cam reveals best fabric combos for cloth masks
Researchers have used high-speed videos of a person sneezing to identify the optimal cloth mask design.
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Milk protein could help boost blueberries' healthfulness
Pairing blueberry pie with a scoop of ice cream is a nice summer treat. Aside from being tasty, this combination might also help people take up more of the 'superfruit's' nutrients, such as anthocyanins. Researchers show that a protein found in cow's milk helped rats absorb more blueberry anthocyanins and their byproducts, boosting accessibility to these good-for-you nutrients.
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Seeking a treatment for IBS pain in tarantula venom
For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.
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Pleistocene sediment DNA from Denisova Cave
Researchers have analyzed DNA from 728 sediment samples from Denisova Cave. Their study provides unprecedented detail about the occupation of the site by both archaic and modern humans over 300,000 years. The researchers detected the DNA of Neandertals and Denisovans, the two forms of archaic hominins who inhabited the cave, and the DNA of modern humans who appeared around the time of the emergence of an archaeological culture called the Initial Upper Paleolithic around 45,000 years ago.
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Tuckered out: Early Antarctic explorers underfed their dogs
New research analyzing a century-old dog biscuit suggests early British Antarctic expeditions underfed their dogs.
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River flow: New machine learning methods could improve environmental predictions
Machine learning algorithms do a lot for us every day -- send unwanted email to our spam folder, warn us if our car is about to back into something, and give us recommendations on what TV show to watch next. Now, we are increasingly using these same algorithms to make environmental predictions for us.
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Mongooses solve inequality problem
A fair society has evolved in banded mongooses because parents don't know which pups are their own, new research shows.
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Sneeze cam reveals best fabric combos for cloth masks
Researchers have used high-speed videos of a person sneezing to identify the optimal cloth mask design.
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Milk protein could help boost blueberries' healthfulness
Pairing blueberry pie with a scoop of ice cream is a nice summer treat. Aside from being tasty, this combination might also help people take up more of the 'superfruit's' nutrients, such as anthocyanins. Researchers show that a protein found in cow's milk helped rats absorb more blueberry anthocyanins and their byproducts, boosting accessibility to these good-for-you nutrients.
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Seeking a treatment for IBS pain in tarantula venom
For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.
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Half of young adults with COVID-19 have persistent symptoms 6 months after, study finds
A new paper describes persistent symptoms six months after acute COVID-19, even in young home isolated people. The most common symptoms were loss of smell and/or taste, fatigue, shortness of breath, impaired concentration, and memory problems.
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AI to track cognitive deviation in aging brains
Researchers have developed an artificial intelligence-based brain age prediction model to quantify deviations from a healthy brain-aging trajectory in patients with mild cognitive impairment, according to a new study. The model has the potential to aid in early detection of cognitive impairment at an individual level.
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Protein linked to heart health, disease a potential therapeutic target for dementia
Researchers have found that high levels of a normal protein associated with reduced heart disease also protect against Alzheimer's-like damage in mice, opening up new approaches to slowing or stopping brain damage and cognitive decline in people with Alzheimer's.
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Language trade-off? No, bilingual children reliably acquire English by age 5
A new study in U.S.-born children from Spanish-speaking families finds that minority language exposure does not threaten the acquisition of English by children in the U.S. and that there is no trade-off between English and Spanish. Rather, children reliably acquire English by age 5, and their total language knowledge is greater to the degree that they also acquire Spanish. Children's level of English knowledge was independent of their level of Spanish knowledge.
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Tuesday, June 22, 2021
Self-reported declines in cognition may be linked to changes in brain connectivity
A research team recently published the results of a three-year study of cognitive changes in older adults who complained that their cognitive ability was worsening though clinical assessments showed no impairments. The MRI studies showed significant changes in functional connectivity in two areas of the brain.
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How pancreatic cancer cells dodge drug treatments
Pancreatic cancer cells typically rely on a mutant version of the KRAS protein to proliferate. These cancer cells can also survive losing KRAS by activating alternative growth pathways. Scientists discovered a new interaction between mutant KRAS and a protein complex called RSK1/NF1 that may be the source of this adaptive resistance.
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Scientists identify combination of biological markers associated with severe dengue
Researchers have identified a combination of biological markers in patients with dengue that could predict whether they go on to develop moderate to severe disease.
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Personality traits relate to being a morning or evening person
The link between the different hierarchies of personality, sleep patterns and even genetics has now been discovered.
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Inherited risk of early-onset cancer is higher among minority families
A new study shows inherited risk of early-onset cancer is significantly higher among Latino and African American families for solid tumors, and Asian/Pacific Islander families for blood-based cancers, compared to non-Latino white families in California. Researchers used California population-based health registries to evaluate the relative cancer risk among first-degree relatives of patients diagnosed with cancer by the age of 26. This study demonstrates the need for increased scrutiny on familial cancer clustering in minority populations.
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Flash mob in the nucleus
The nucleus is much more than a storage compartment for chromosomes: It also contains the complex machinery producing transcripts of the genes that are currently needed and releases them into the cell body. Some of the proteins involved herein are not evenly distributed in the nucleus, but cluster at specific sites. A study now shows how these 'flash mobs' are regulated.
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Ready, set, go - how stem cells synchronize to repair the spinal cord in axolotls
Few animals can regenerate their spinal cord after an injury. The axolotl can mobilize stem cells in its spinal cord to regrow the lost tissue. An international team of scientists have investigated the early stages of this process.
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Salt marsh plants may signal carbon capture capacity
Coastal wetlands like seagrass meadows, mangroves, and salt marshes play vital roles along the shoreline, from providing a buffer against storm surges, to providing critical habitat for animals, to capturing atmospheric carbon. We are still just beginning to comprehend the intricate workings of these highly productive ecosystems and their role in mitigating the climate crisis, but researchers are one step closer to understanding how salt marsh vegetation, their bacterial communities, and vegetation can help predict a marsh's potential to be a blue carbon reservoir.
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Crab species found to have asymmetrical male and female reproductive structures
Researchers have recently identified and described a new genus and species of xanthid crab found in Okinawa Island, Ryukyu Islands, Japan. Named Mabui calculus, it is the first among the 7,800 species of known crabs to have strongly asymmetrical male and female reproductive structures.
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Boost for mouse genetic analysis
To understand what role an individual gene plays, biologists have, for 100 years, been using a trick of nature: While in principle, the genome in all cells of an organism is the same, mutations arise in individual cells. These mutations differentiate a cell from its neighbors, forming a 'genetic mosaic.' Now, researchers have advanced genetic mosaic analysis, making almost all genes in the mouse genome accessible to single-cell genetic mosaic analysis.
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Sports: Men and women react differently to a missing audience
Without an audience, men run slower and women faster: The lack of spectators during the coronavirus pandemic appears to have had a noticeable effect on the performance of athletes at the 2020 Biathlon World Cup, a new study shows. According to the new analysis, women also performed better in complex tasks, such as shooting, when an audience was present while men did not.
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Secretin hormone induces satiation by activating brown fat
Researchers have discovered a new mechanism controlling satiation. According to the recently published study, the hormone secretin induces satiation by activating brown adipose tissue.
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AR can improve the lives of older adults, so why are apps designed mainly for youngsters?
Older people affected by memory loss have much to gain from AR technology, yet a study exploring the use of augmented reality to support older adults at home finds the user interface is sometimes confusing for those aged 50+.
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Childhood trauma can make people like morphine more
People who have experienced childhood trauma get a more pleasurable 'high' from morphine, new research suggests.
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Open learning spaces do not increase children's physical activity
According to a recent study, open learning spaces are not directly associated with the physical activity of students in grades 3 and 5, even though more breaks from sedentary time were observed in open learning spaces compared to conventional classrooms.
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Mushroom growing out of fossilized ant reveals new genus and species of fungal parasite
Oregon State University research has identified the oldest known specimen of a fungus parasitizing an ant, and the fossil also represents a new fungal genus and species.
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Cohesin opens up for cell division
Scientists have uncovered a mechanism that allows a protein complex to bind to DNA without impeding some of the important processes of cell division. Their findings could further understandings of developmental disorders arising from mutations in the gene that codes for the complex.
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Boost for mouse genetic analysis
To understand what role an individual gene plays, biologists have, for 100 years, been using a trick of nature: While in principle, the genome in all cells of an organism is the same, mutations arise in individual cells. These mutations differentiate a cell from its neighbors, forming a 'genetic mosaic.' Now, researchers have advanced genetic mosaic analysis, making almost all genes in the mouse genome accessible to single-cell genetic mosaic analysis.
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Illuminating the mechanism behind how plants regulate starch synthesis
Biologists have used rice to successfully illuminate the mechanism by which plants regulate the amount of starch produced via photosynthesis. This knowledge could contribute towards improving the quality and yield of agricultural crops.
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Producing hydrogen using less energy
The way in which a compound inspired by nature produces hydrogen has now been described in detail. These findings are the foundation for the energy-efficient production of hydrogen as a sustainable energy source.
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The humidity of flowers acts as an invisible attractor for bumblebees
As well as bright colors and subtle scents, flowers possess many invisible ways of attracting their pollinators, and a new study shows that bumblebees may use the humidity of a flower to tell them about the presence of nectar.
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Venomous caterpillar has strange biology
The venom of a caterpillar, native to South East Queensland, shows promise for use in medicines and pest control, researchers say.
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Study shows brain differences in interpreting physical signals in mental health disorders
Researchers have shown why people with mental health disorders, including anorexia and panic disorders, experience physical signals differently.
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Monday, June 21, 2021
New research finds link between walking speed and dual tasking after stroke
Research has found that training stroke survivors to walk at a faster speed during recovery can help improve the brain function that enables people to walk and perform another task simultaneously, known as dual-task walking.
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Targeted therapy could be first line treatment for childhood cancer
Scientists studying a common childhood cancer have made a major breakthrough which could lead to a cure for some youngsters who would not have survived the condition.
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Adjuvant-free avian influenza vaccines in the works
Researchers develop a new avian influenza vaccine using plant-based recombinant protein.
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Microscopy deep learning predicts viral infections
When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy. Using fluorescence images from live cells, researchers have trained an artificial neural network to reliably recognize cells that are infected by adenoviruses or herpes viruses. The procedure also identifies severe acute infections at an early stage.
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Summer catch-up programs need to focus on teens' wellbeing, not just academic progress
Summer holiday school catch-up programs to address gaps in knowledge after school closures need to support children who are still struggling due to social isolation.
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Cellular mechanisms of early mammary gland development unraveled
A research group used live tissue imaging for the first time to visualize the emergence of the mammary gland.
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Twenty-year study links childhood depression to disrupted adult health and functioning
Depression in youth, between the ages of 10 and 24 years, is both a leading cause of stress and a possible risk factor for future diseases and impairment. Now, a study confirms that depression in childhood or adolescence is associated with higher levels of adult anxiety and substance use disorders, worse health and social functioning, less financial and educational achievement, and increased criminality.
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Scientists reveal silver-based antimicrobials can be utilized as antibiotic adjuvants to combat antibiotic-resistant Staphylococcus aureus
A research team discovers that silver (Ag)-based antimicrobials can effectively combat antibiotic resistant Staphylococcus aureus by targeting multiple biological pathways via functional disruption of key proteins and can be further exploited to enhance the efficacy of conventional antibiotics as well as to resensitize methicillin-resistant Staphylococcus aureus (MRSA) to antibiotics.
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COVID-19 dual-antibody therapies effective against variants in animal study
A new study suggests that many, but not all, COVID-19 therapies made from combinations of two antibodies are effective against a wide range of virus variants. Further, combination therapies appear to prevent the emergence of drug resistance.
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Antibody disease enhancement of COVID-19 does not appear to occur in animal models
Researchers have demonstrated in mice and monkeys that human antibodies lacked the ability to make SARS-CoV-2 infection worse and, instead, exerted their defensive powers against the infection. The findings help reinforce evidence that antibodies are safe when given as treatments or induced by COVID-19 vaccines.
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Scientists develop energy saving technique paving way for a carbon neutral society
Researchers have discovered a method which will allow for faster communication systems and better energy saving electronics.
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Projections of US high-tide flooding show rapid increases and extreme months
In the mid-2030s, multiple United States coastal regions may see rapid increases in the number of high-tide flooding (HTF) days, according to a new study. The combined effects of sea-level rise and natural fluctuations in tidal range are anticipated to cause tipping points in the frequency of HTF.
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Targeted therapy could be first line treatment for childhood cancer
Scientists studying a common childhood cancer have made a major breakthrough which could lead to a cure for some youngsters who would not have survived the condition.
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Adjuvant-free avian influenza vaccines in the works
Researchers develop a new avian influenza vaccine using plant-based recombinant protein.
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Microscopy deep learning predicts viral infections
When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy. Using fluorescence images from live cells, researchers have trained an artificial neural network to reliably recognize cells that are infected by adenoviruses or herpes viruses. The procedure also identifies severe acute infections at an early stage.
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Cellular mechanisms of early mammary gland development unraveled
A research group used live tissue imaging for the first time to visualize the emergence of the mammary gland.
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Scientists reveal silver-based antimicrobials can be utilized as antibiotic adjuvants to combat antibiotic-resistant Staphylococcus aureus
A research team discovers that silver (Ag)-based antimicrobials can effectively combat antibiotic resistant Staphylococcus aureus by targeting multiple biological pathways via functional disruption of key proteins and can be further exploited to enhance the efficacy of conventional antibiotics as well as to resensitize methicillin-resistant Staphylococcus aureus (MRSA) to antibiotics.
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There's more to genes than DNA: How Mum and Dad add something extra, just for you
Biologists have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics - an area of science that describes how genes are switched on (and off) in different cells, at different stages in development and adulthood.
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Computers help researchers find materials to turn solar power into hydrogen
Researchers report that they have taken a step toward overcoming the challenge of inexpensive hydrogen production by using supercomputers to find materials that could help accelerate hydrogen separation when water is exposed to light, a process called photocatalysis.
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Engineers create 'seeds' for growing near-perfect 2D perovskite crystals
Engineers have created microscopic seeds for growing remarkably uniform 2D perovskite crystals that are both stable and highly efficient at harvesting electricity from sunlight.
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There's more to genes than DNA: How Mum and Dad add something extra, just for you
Biologists have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics - an area of science that describes how genes are switched on (and off) in different cells, at different stages in development and adulthood.
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New modeling technique shows greater likelihood, frequency of urban extreme heat events
This model addresses the fact that most traditional climate models effectively ignore cities entirely, causing them to underestimate the frequency and severity of urban heat waves. Urban areas make up only 2-3% of the earth's land, so their effect on global models is negligible, but more than half of the world's population lives in urban areas, so their impact is significant.
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A bright future: Using visible light to decompose CO2 with high efficiency
To tackle the challenge of global warming, scientists have been looking into green and sustainable methods of breaking down carbon dioxide in emissions and in the atmosphere. Now, a group of researchers have developed a novel, easy to synthesize composite compound that enables the efficient use of solar energy to reduce carbon dioxide, taking us one step closer to achieving a green economy.
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mRNA vaccine yields full protection against malaria in mice
Scientists developed an mRNA vaccine that protects against malaria in animal models. Malaria remains a large public health and economic burden worldwide as well as a danger to deployed Service Members. This vaccine uses mRNA accompanied by a lipid nanoparticle to prompt cells to code for circumsporozoite protein, which then triggers an immune response against malaria. The vaccine achieved high levels of protection in mice, encouraging further development for the novel platform.
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New geochemical study confirms cause of end-Permian mass extinction event
Researchers found a direct link between global dispersion of nickel-rich aerosols, ocean chemistry changes and the end-Permian mass extinction event that took place 251 million years ago.
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Smaller bodies, longer wings, earlier migrations: Untangling the multiple impacts of climate warming
When a research team reported last year that North American migratory birds have been getting smaller over the past four decades and that their wings have gotten a bit longer, the scientists wondered if they were seeing the fingerprint of earlier spring migrations.
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mRNA vaccine yields full protection against malaria in mice
Scientists developed an mRNA vaccine that protects against malaria in animal models. Malaria remains a large public health and economic burden worldwide as well as a danger to deployed Service Members. This vaccine uses mRNA accompanied by a lipid nanoparticle to prompt cells to code for circumsporozoite protein, which then triggers an immune response against malaria. The vaccine achieved high levels of protection in mice, encouraging further development for the novel platform.
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New software for designing sustainable cities
By 2050, more than 70% of the world's population will live in cities. Researchers have developed software that shows city planners where to invest in nature to improve people's lives and save billions of dollars.
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Sunday, June 20, 2021
Saturday, June 19, 2021
New therapeutic target for C. difficile infection
A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.
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Researchers review data on reputed toxins thought to cause neurodegeneration
Biologists and neuroscientists have published an update on the reputed environmental toxins that have been suspected of being involved in mammal neurodegeneration.
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Imaging at the tip of a needle
Scientists have developed a new technique that could revolutionize medical imaging procedures using light.
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New evidence to battle drug price increases
Two recent studies add new evidence to the impact of how drug price increases affect US patients and the overall cost of health care.
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Use rewards effectively to boost creativity
To boost employees' creativity, managers should consider offering a set of rewards for them to choose from, according to a new study.
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Will reduction in tau protein protect against Parkinson's and Lewy body dementias?
Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias? A new study suggests the answer is no. If this is borne out, that result differs from Alzheimer's disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease -- and thus suggests that the role of tau in the pathogenesis of Lewy body dementias is distinct from Alzheimer's disease.
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Bio-inspired hydrogel protects the heart from post-op adhesions
A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents. The team of engineers, scientists and physicians also conducted a pilot study on porcine hearts, with promising results.
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Researchers review data on reputed toxins thought to cause neurodegeneration
Biologists and neuroscientists have published an update on the reputed environmental toxins that have been suspected of being involved in mammal neurodegeneration.
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Earlier flood forecasting could help avoid disaster in Japan
Researchers have revealed that a newly developed forecasting system can accurately predict flood locations 32 hours in advance. Extreme rainfall events are occurring increasingly frequently; such accurate and timely flood warnings will help to minimize their impact by providing time for measures to protect people and property.
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Start-stop system of hunting immune cells
Researchers decipher the basic biology of neutrophil swarming and now show that the cells also evolved an intrinsic molecular program to self-limit their swarming activity. The study elucidates how swarming neutrophils become insensitive to their own secreted signals that brought the swarm together in the first place. This process is crucial for the efficient elimination of bacteria in tissues.
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How cells 'read' artificial ingredients tossed into genetic recipe
Researchers discovered that the enzyme RNA polymerase II recognizes and transcribes artificially added base pairs in genetic code, a new insight that could help advance the development of new vaccines and medicines.
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Dragonflies: Species losses and gains in Germany
Over the past 35 years, there have been large shifts in the distributions of many dragonfly species in Germany. Those of standing water habitats have declined, probably due to loss of habitat. Running-water species and warm-adapted species have benefited from improved water quality and warmer temperatures. The study highlights the importance of citizen science and natural history societies for long-term data collection.
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Phytoplankton: The discovery of a missing link
Biologists have identified a family of algae as a living missing link in the microscopic domain.
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Climate warming can influence fungal communities on oak leaves across the growing season
Climate warming plays a larger role than plant genes in influencing the number and identity of fungal species on oak leaves, especially in autumn. This research by ecologists sheds light on how warming and tree genes affect the dynamics of fungal communities across the season.
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New cause for intensification of oyster disease
Researchers reveal that intensification of major oyster disease was due to evolving parasite, not just drought as previously thought.
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Start-stop system of hunting immune cells
Researchers decipher the basic biology of neutrophil swarming and now show that the cells also evolved an intrinsic molecular program to self-limit their swarming activity. The study elucidates how swarming neutrophils become insensitive to their own secreted signals that brought the swarm together in the first place. This process is crucial for the efficient elimination of bacteria in tissues.
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How cells 'read' artificial ingredients tossed into genetic recipe
Researchers discovered that the enzyme RNA polymerase II recognizes and transcribes artificially added base pairs in genetic code, a new insight that could help advance the development of new vaccines and medicines.
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Friday, June 18, 2021
In the visual thalamus, neurons are in contact with both eyes but respond to only one
The visual thalamus is classically known to relay visual stimuli coming from the retina to the cerebral cortex. Researchers now show that although neurons in the mouse visual thalamus connect to both eyes, they establish strong functional connections only with one retina. These results settle partly contradictory results of earlier studies and demonstrate how important it can be to complement structural data with functional analyses.
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Altered microstructure improves organic-based, solid state lithium EV battery
Researchers improve energy density in a novel electric vehicle battery - a step toward a more cost-effective, easily recycled battery that would allow EVs to travel farther and charge faster at a low cost.
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Sacred natural sites protect biodiversity in Iran
How much do traditional practices contribute to the protection of local biodiversity? Why and how are sacred groves locally valued and protected, and how can this be promoted and harnessed for environmental protection? Researchers have examined the backgrounds of this form of local environmental protection in Baneh County, Iran.
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Memory helps us evaluate situations on the fly, not just recall the past
Scientists have long known the brain's hippocampus is crucial for long-term memory. Now a new study has found the hippocampus also plays a role in short-term memory and helps guide decision-making. The findings shed light on how the hippocampus contributes to memory and exploration, potentially leading to therapies that restore hippocampal function, which is impacted in memory-related aging and neurodegenerative diseases such as dementia, the study authors said.
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How childhood exercise could maintain and promote cognitive function in later life
People who are physically active during childhood have higher cognitive functions in later life. Participants who exercised when they were children did better on cognitive tests regardless of their current age. However, no such relationship was found between task performance and post-childhood exercise -- suggesting that exercise during childhood is particularly important for brain development and long-term cognitive health.
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Science-based hiccups intervention
A science-based intervention relieved hiccups for 92% of 249 users who self-reported the effectiveness of the tool. =
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Researchers translate a bird's brain activity into song
It is possible to re-create a bird's song by reading only its brain activity, shows a first proof-of-concept study. The researchers were able to reproduce the songbird's complex vocalizations down to the pitch, volume and timbre of the original. The study is a first step towards developing vocal prostheses for humans who have lost the ability to speak.
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Animals' ability to adapt their habitats key to survival amid climate change
A research group of scientists from North America, Europe and Africa concluded that animals' ability to respond to climate change likely depends on how well they modify their habitats, such as nests and burrows.
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Footprints discovered from the last dinosaurs to walk on UK soil
Footprints from at least six different species of dinosaur -- thought to be the very last dinosaurs to walk on UK soil 110 million years ago -- have been found in Kent.
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